2021 AMI Online Salon

View into a Synapse to Feature the Release of GABA, and its Binding to the Pentameric GABA Receptors

Project Details

  • Entrant Name:  Audra Geras
  • Client: Alacrity Consulting
  • Copyright: Audra Geras, 2020
  • Medium/software used: ZBrush, XSI, Keyshot, Photoshop
  • Final presentation format: Multiple marketing uses including print, web and large format
  • Primary Audience: Pain Management Professionals

Project Description

The intended purpose was to create a dramatic view into a synapse to show the release of GABA neurotransmitter molecules from the presynaptic vesicles and membrane, and then the subsequent binding of GABA to its pentameric receptors on the postsynaptic membrane. This is important to pain management professionals because binding of GABA may exert an inhibitory effect on pain signals and a number of drug therapies either promote the binding of GABA, or are believed to have a similar mode of action.