2021 AMI Online Salon

Lumbar puncture explained: Unlocking the mysteries of Alzheimer’s disease

Project Detail

  • Entrant Name:  Jason Sharpe
  • Other Contributors:  Sonya Amin, Susan Park
  • Client: Banner Health
  • Copyright: AXS Studio, 2020
  • Medium/software used: 
  • Final presentation format: HD video
  • Primary Audience: Alzheimer’s disease patients and caregivers

Project Description

Understanding how Alzheimer’s disease (AD) attacks the brain can help researchers develop earlier detection methods and stronger treatments. One of the safe ways to study AD is by analyzing the cerebrospinal fluid (CSF) of patients obtained by lumbar puncture (LP). Our client needed a concise, patient-friendly video to inspire AD patients to overcome LP hesitancy and donate CSF to research. We approached this from a patient perspective and developed a calm visual style, with a sensitive depiction of the main character, who may be experiencing cognitive impairment or dementia. We consulted AD researchers and numerous references to depict the LP procedure accurately and sensitively. Proteins were modeled using structural data and rendered at a patient-friendly level of detail. Design decisions around pacing, language, iconography and typography balanced the needs of an audience with cognitive and memory impairments with visual interest, credibility and reassurance for caregivers.