2021 AMI Online Salon

HFE-Related Hereditary Hemochromatosis Poster

Project Details

  • Entrant Name:  Delaney Maxwell
  • Client:University of Illinois, Chicago
  • Copyright: Delaney Maxwell, 2021
  • Medium/software used:3ds Max, Mudbox, Photoshop
  • Final presentation format:PDF
  • Primary Audience:Medical professionals

Project Description

Hemochromatosis is a disease characterized by “iron-overload,” or a toxic accumulation of iron in the body, with HFE-related hereditary hemochromatosis being the most common form.  This “HFE-related Hereditary Hemochromatosis Poster” highlights the origin of the disease, which is a C282Y mutation in the HFE gene within HLA-A on chromosome 6. This mutation results in a lack of hepcidin production from hepatocytes, leading to iron overload and eventually causing hemochromatosis. The poster was created with the intention of being presented to a biomedical professional audience, as well as to those affected by the disease, in order to provide a clear and aesthetically pleasing explanation on what causes HFE-related hereditary hemochromatosis, as well as the symptoms and effects of the disease.