2021 AMI Online Salon

BiTE® Immuno-oncology platform

Project Detail

  • Entrant Name:  Jason Sharpe
  • Other Contributors:  Eddy Xuan, Lima Colati
  • Client: Amgen
  • Copyright: Amgen, 2020
  • Medium/software used: Autodesk Maya, HTML5, JavaScript, Adobe Illustrator
  • Final presentation format: Responsive website
  • Primary Audience: Healthcare providers

Project Description

With conferences pushed online by the pandemic, our client faced a significant communication challenge: they needed to convey the mechanism of action (MOA) and versatility of their BiTE immuno-oncology platform within a virtual exhibit booth in a way that engaged healthcare providers and ran smoothly on desktop and mobile browsers. We created an experience that lets users explore 4 distinct tumor microenvironments, running simulations to see BiTE molecules engage target cancer cells. We accomplished this using WebGL, a JavaScript API for web-based interactive 3D graphics. Users rotate and zoom in to the 3D models to access ‘factoids’ and see BiTE’s MOA from different vantage points. Anatomical models were based on histological data and optimized for WebGL, while the scale of BiTE molecules and target receptors was exaggerated for clear identification. A bold color palette and simplified textures invites participants to explore and helps easily discern different cells and molecules.